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Alzheimer's Disease Research
Added ›07/12/2010 2:12:11 PM

Hallmark Alzheimer's Disease Changes Found In Retinas Of Humans And Imaged In Live Animals

July 6, 2010

Adapted from Cedars-Sinai Medical Center

The nerve cell-damaging plaque that builds up in the brain with Alzheimer’s disease also builds up in the retinas of the eyes—and it shows up there earlier, leading to the prospect that noninvasive optical imaging of the eyes could lead to earlier diagnosis, intervention and monitoring of the disease, according to new research.

Scientists discovered characteristic amyloid plaques in retinas from deceased Alzheimer’s disease patients and used a noninvasive optical imaging technique to detect retinal plaques in live laboratory mice genetically modified to model the human disease. The combined results suggest the possibility that noninvasive retinal imaging may be helpful in early diagnosis of the disease.

The research was conducted by a team of scientists at Cedars-Sinai Medical Center in collaboration with colleagues from the Weizmann Institute of Science in Israel and the University of Southern California. Results were published online June 13 in the journal NeuroImage. Alzheimer’s disease is a devastating condition that is becoming more prevalent worldwide as the baby boom generation advances into its senior years, but there is no conclusive, noninvasive way to diagnose it. Previous studies have suggested that changes in the brain may begin years or even decades before symptoms occur—emphasizing the need for earlier, reliable detection for early therapeutic intervention to achieve effective remedy. The new study suggests the possibility of monitoring Alzheimer’s disease through a simple retinal imaging approach.

Abnormal deposits in the brain called beta-amyloid plaques, which damage cells and interrupt cell-to-cell communications, are recognized as a hallmark sign of the disease. However, because existing noninvasive brain-imaging technologies cannot provide sufficient detail about these changes, the most definitive diagnosis of Alzheimer’s disease comes after an autopsy.

The research team considered the retina a better target for noninvasive imaging of Alzheimer’s disease because it is readily accessible and, unlike other components of the eye, it is part of the central nervous system, having a direct connection and thus many similarities with the brain. Previous studies have documented non-specific visual disturbances, eye disorders and certain types of retinal abnormalities occurring with Alzheimer’s disease and other neurodegenerative conditions, but this is the first to identify human retinal plaque deposits that could provide a specific diagnostic marker of Alzheimer’s disease.

Among the new findings:

  • In lab tests, plaques in the retinas of mice genetically modified to model Alzheimer’s disease could be detected at a very early, pre-symptomatic stage – before the plaque appeared in the brain.

  • A high-resolution, noninvasive optical imaging approach was developed to monitor individual beta amyloid plaques in the retinas of live mice. The system is based on a harmless specific marker and the adaptation of an existing optical system used to examine rodent eyes.

  • The research team used a fluorescent compound called curcumin to label and detect retinal plaques. This is believed to be the first use of curcumin as an imaging agent to detect Alzheimer’s disease-related plaques in the retinas of live animals. Curcumin, a natural component of the spice turmeric, binds to beta-amyloid plaques and makes them visible when viewed microscopically. In the Cedars-Sinai research, curcumin injected into the bloodstream of live mice crossed the blood-retinal barrier and specifically bound to the retinal plaques, allowing them to be viewed in high resolution with a noninvasive procedure.

  • Observations from multiple genetically engineered mouse models of Alzheimer’s disease demonstrated a correlation between retinal plaques and brain plaques as disease progressed.

  • In the laboratory mice, a unique immune system-based therapy that reduces the amount of plaques in the brain also reduced plaque load in the retina to the same extent, suggesting that the retina could faithfully represent the brain in assessing response to therapy.

  • Beta-amyloid plaques were identified in retinal samples from human patients who had died from Alzheimer’s disease, and their features correlated with the diagnosed stage of the disease. Importantly, plaques were clearly detected not only in patients who definitely had the disease, but also in the retinas of some people who were suspected of having early-stage Alzheimer’s disease based on clinical diagnosis and microscopic examination of brain tissue after death.

Together, the results offer the first evidence for the existence of Alzheimer’s-specific plaques in the retina of human patients and the ability to detect individual plaques in live mouse models, creating a strong basis for future research building on these findings. According to the authors, these studies establish the potential of direct retinal beta-amyloid plaque imaging in live subjects as a tool for early Alzheimer’s disease diagnosis and prognosis, as well as assessment of therapies.

View all news updates for Alzheimer's disease


Disclaimer: The information provided in this section is a public service of the American Health Assistance Foundation, and should not in any way substitute for the advice of a qualified healthcare professional and is not intended to constitute medical advice. Although we take efforts to keep the medical information on our website updated, we cannot guarantee that the information on our website reflects the most up-to-date research. Please consult your physician for personalized medical advice; all medications and supplements should only be taken under medical supervision. The American Health Assistance Foundation does not endorse any medical product or therapy.

Some of the content in this section is adapted from other sources, which are clearly identified within each individual item of information.

Training for Senior Citizens and Jobs in Community Service
Added ›07/12/2010 9:45:32 AM

of Labor announces nearly $597 million in continued funding to support community service-based job training programs for seniors

WASHINGTON — The U.S. Department of Labor today released $596,525,000 in funds to continue support for 74 state, territory and national grantees of the Senior Community Service Employment Program for program year 2010. These funds will enable income and training support for 61,900 individuals ages 55 and older, who have low incomes or are unemployed. At least 75 percent of SCSEP funds will go to provide these individuals with part-time, paid community service-based job training program opportunities throughout the country.

"Older workers are an essential part of our nation's present and an increasingly greater part of its future, but it can be difficult for this dynamic sector of our population to access good jobs," said Secretary of Labor Hilda L. Solis. "At the U.S. Department of Labor, we are committed to ensuring older workers have access to the training and other professional services they both need and deserve. The SCSEP program assists participants in enhancing their marketability and allows them the opportunity to further contribute to their communities."

Through this program, participants will provide more than 40 million hours of community service to public agencies and nonprofit organizations annually. Grant awards are being made to all 50 states, the District of Columbia, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands and the U.S. Virgin Islands, as well as 18 national nonprofit organizations. SCSEP services are available in every county in the U.S.

Funds are being awarded to each state either directly or through one of the following 18 national organizations: AARP Foundation; Asociacion Nacional Pro Personas Mayores; Easter Seals Inc.; Experience Works Inc.; Goodwill Industries International Inc.; Institute for Indian Development Inc.; Mature Services Inc.; National Able Network Inc.; National Asian Pacific Center on Aging; National Caucus and Center on Black Aged Inc.; National Council on the Aging Inc.; National Indian Council on Aging Inc.; National Urban League; Quality Career Services Inc.; SER Job for Progress National Inc.; Senior Service America Inc.; Vermont Associates for Training Development Inc.; and The Work Place Inc.

Editor's Note: A chart reflecting the dollar amounts benefiting each state follows this news release.



STATE

SCSEP ALLOCATION

Alabama

10,818,394

Alaska

2,553,380

Arizona

8,474,542

Arkansas

11,361,238

California

50,001,649

Colorado

5,919,045

Connecticut

6,409,440

Delaware

2,553,380

District of Columbia

3,360,134

Florida

34,446,010

Georgia

13,092,991

Hawaii

2,553,380

Idaho

2,878,354

Illinois

22,714,367

Indiana

15,285,606

Iowa

7,477,709

Kansas

5,797,794

Kentucky

11,070,918

Louisiana

10,079,713

Maine

3,602,911

Maryland

8,031,271

Massachusetts

12,721,542

Michigan

18,762,904

Minnesota

13,896,731

Mississippi

7,545,259

Missouri

14,120,529

Montana

3,641,765

Nebraska

4,350,782

Nevada

2,992,869

New Hampshire

2,878,354

New Jersey

Delicious Orchards Bus Trip Sept. 21,2010!!!
Added ›06/30/2010 11:33:05 AM
Brick Senior Center will be offering a bus trip to Delicious Orchards on Tuesday, September 21st.  Please call 732-920-8686 for information on this event. 
Solar Panels Paying off for Township
Added ›06/30/2010 9:14:36 AM

Mayor Stephen Acropolis and the Township Council will be presented with a check from Knollwood Energy, LLC at tonight’s Council Meeting for Solar Renewable Energy Credits that were produced by the solar panel system at the Brick Township Municipal Building.

 

“This is the first of many checks that we are going to get thanks to our solar power system,” said Mayor Acropolis.  “The revenue that is going to be generated over the next fifteen years is going to be invaluable and help us provide services to the people of Brick Township.”

 

Earlier this month, Knollwood Energy was awarded a 3 year contract to purchase the SRECs from the Township.  The $22,274 check is payment for 37 SRECs produced from the time the system went operational in earlier this year until May 31, 2010.  The Town expects to receive about $77,000 a year over the next three years from the sale of SRECs and produce another $30,000 in savings annually on electricity at the municipal building.

 

Last year, the Township installed a 125kw photovoltaic roof mounted solar system and a 12kw ground mounted photo photovoltaic solar system at the municipal complex.  The installation was completed earlier this year. The system will produce about 158,511 kWh annually.  The project cost $765,000, approximately $235,000 under what was budgeted.  It was funded through the 2009 Capital Budget.  The contractor was Barrier Electric of Bayonne, NJ.

 

The solar photovoltaic project was born out of the township’s comprehensive Sustainable Energy Master Plan (SEMP) that was developed by Birdsall Services Group with input from the MACRE.  Future projects that are part of the SEMP include the installation of a wind turbine at the Drum Point Sports Complex that could generate 30,000 kilowatts of electricity and the construction of a solar field at the site of the French’s Landfill.

 

# # #

Mayor and Council Discuss Referendums for Municipal Services
Added ›06/30/2010 9:13:59 AM

Mayor Stephen Acropolis and the Township Council plan on giving voters the opportunity to decide how services will be provided by the municipality in the future by placing referendum questions on this November’s ballot.  The questions will ask voters opinions on services ranging from police and public safety to solid waste collection.

 

“It was a challenge to put together a budget that fit within the state’s budgetary and tax levy caps while not cutting services this year,” said Mayor Acropolis.  “This is likely not going to be possible moving forward.  The caps are going to be more restrictive next year and costs to provide services are going to continue to rise.  We are going to ask the people how they want services delivered and how they want to pay for them.”

 

The Township Administration is going to work with the Township Council and legal counsel to develop non-binding referendum questions for this November’s ballot.  The questions will ask voters opinion on various Township services and funding levels for those services.  The questions are going to be a continuation of the administration and council’s efforts to transform the local government in Brick Township.

 

“We have been working to move Brick Township to a more user-based system of governance.  People who use services, programs and facilities should shoulder a larger burden of the cost of them than those who do not use them,” said Mayor Acropolis.  “These ballot questions will give the public their chance to weigh in and let us know if they want us to continue to change the way the township does business.”

 

“We are going through tough economic times.  It is happening in communities throughout the State,” said Council President Anthony Matthews.  “We are going to have to face this as an entire community and get through it together.  Having it placed on the ballot will let the people know what is going on and have their say.  We are going to involve the public in this just like we have been doing since 2004.”

 

The referendum questions are being placed on the ballot to give the Mayor and Council a clearer idea of what services that the voters deem essential and how they want those services to be funded through taxation or other means, such as user-based fees.  Voters will be asked their opinion on topics such as whether or not the Township should maintain municipal garbage collection or use a private service.

 

“We are going to give the people the chance to effect change in municipal government,” said Mayor Acropolis.  “They are going to have the opportunity to set the standard for reform in New Jersey.”

 

Mayor Acropolis says that State mandated tax levy and spending caps are necessitating this reform.  “Our leaders in Trenton, most notably Governor Christie, are working to bring change to New Jersey and make it more affordable.  We are working to follow his lead and make Brick Township more affordable through institutional changes.”  Mayor Acropolis cites staff reduction and health care contributions as initiatives that will have permanent impacts on municipal spending.

 

Municipal governments currently operate under a 4% tax levy cap.  The state legislature recently approved a 2.9% tax levy cap and Governor Christie is proposing a constitutionally mandated 2.5% tax levy cap with no exemptions.

 

“This Council has been cutting for years.  We have worked with the Mayor to reduce the size of our staff and rein in municipal spending while not affecting services.  It is becoming more likely that we are going to have to affect services in the future,” said Councilwoman Ruthanne Scaturro, Chairwoman of the Business and Finance Committee.  “We are going to ask the people what they are willing to pay for and what they are willing to give up as a community.  Since the people are going to be affected, we are going to let them have their say.”

 

In order to have the questions placed on this November’s ballot, the Township Council must pass a resolution at the August 10th Council Meeting.  The questions must be submitted to the County Clerk no later than August 20.

 

The Township will seek the input of the Citizens Budget Advisory Committee while drafting the referendum questions.  “Our Citizens Budget Advisory Committee members have put in a great deal of time learning about our budget and the issues that are impacting it,” said Mayor Acropolis.  “They know what is going on and we are going to ask them to help us as we move forward with these questions and represent the community’s point of view.”

 

Medicare Rebate Alert Checks BE CAREFUL!!!
Added ›06/17/2010 8:58:33 AM

 


 

Be CAREFUL!!!!!!!

 

 

 

$250 Medicare Rebate Checks Alert
 
Target: Medicare Beneficiaries
  The U.S. Health and Human Services agency began mailing $250 Medicare rebate checks last week, also known as the donut hole checks, to the estimated 4 million eligible Medicare beneficiaries.
 

Please note scam artists will be using this opportunity to get
personal information!
 

There are no forms to complete or information to give in
order to receive the $250 rebate check.
Beneficiaries:
Do not provide any personal information or bank account numbers to get the rebate check, and
Do not give any personal information to anyone who calls about the rebate check.
 
Call the Department of Health and Human Services' inspector general to report possible scams: (800) 447-8477.
For more information, visit
www.medicare.gov.

Township Unveils Solar Power System at Municpal Building
Added ›05/28/2010 12:22:05 PM

Mayor Stephen Acropolis was joined by Township officials, representatives of Birdsall Services Group and members of the Mayor’s Advisory Committee on Renewable Energy (MACRE) as they officially unveiled the Brick Township Municipal Building’s solar power system today.

 

“In today’s age of state mandated caps and falling revenues, it is important that towns look for ways to save money,” said Mayor Acropolis.  “These solar panels will reduce the amount of money we spend on utilities at Town Hall.  Every dime we save on our electric bill is one more dime we can put towards maintaining services.”

 

Earlier this year, the installation of a 125kW roof-mounted solar photovoltaic system and a 12kW ground-mounted solar photovoltaic system at Brick Township Municipal Complex was completed.  The system will produce about 158,511 kWh annually.  The project cost $765,000, approximately $235,000 under what was budgeted.  It was funded through the 2009 Capital Budget.  The contractor was Barrier Electric of Bayonne, NJ.

 

“What is great is that between the savings on utilities and the revenue it will generate through solar renewable energy credits this system will pay for itself in a matter of years,” said Mayor Acropolis.

 

Solar renewable energy credits (SRECs).  According to New Jersey Clean Energy Program’s website, each time a system generates 1,000 kWh of electricity, an SREC is earned and placed in the customer's electronic account.  SRECs can then be sold on the SREC tracking system, providing revenue for the first 15 years of the system's life.  The Township anticipates generating about $90,000 a year in revenue through SRECs alone and another $30,000 or so from savings on our electric bills.”

 

“This is a great investment for our community and for our taxpayers,” said Council President Anthony Matthews.  “It is another example of the administration and council working to make sure that our taxpayer dollars are being used wisely and in ways that are going to provide our community with the best return for their hard earned dollars.”

 

The solar photovoltaic project was born out of the township’s comprehensive Sustainable Energy Master Plan (SEMP) that was developed by Birdsall Services Group with input from the MACRE.  Future projects that are part of the SEMP include the installation of a wind turbine at the Drum Point Sports Complex that could generate 30,000 kilowatts of electricity and the construction of a solar field at the site of the French’s Landfill.

 

“The solar field project is one of the most exciting I have been involved with,” said Mayor Acropolis.  “The field will generate about $2.5 million in net revenue every year for the next 15 years, a total of about $37.5 million.  That is money that we can use to maintain services and try to reduce the tax burdens our citizens face everyday.”

 

The Township and Birdsall Services Group are working on a plan that includes an impermeable cap for the landfill and a 24-acre, 7.5 megawatt solar PV field.  When completed, this project along with our other solar PV projects and wind turbine project will make Brick Township one of NJ’s renewable energy leaders.

2010 Standarized Medicare Supplement Plans
Added ›05/27/2010 9:33:43 AM

2010 STANDARDIZED MEDICARE SUPPLEMENT PLANS

A

B

C

D

F             F*

G

K

L

M

N

Hospital Part A coinsurance plus coverage for 365 add’l days after Medicare benefits end,

 

100% Part B coinsurance,

 

First three pints of blood each year

 

Hospice Part A coinsurance

Hospital Part A coinsurance plus coverage for 365 add’l days after Medicare benefits end,

 

100%Part B coinsurance,

 

First three pints of blood each year

 

Hospice Part A coinsurance

Hospital Part A coinsurance plus coverage for 365 add’l days after Medicare benefits end,

 

100% Part B coinsurance,

 

First three pints of blood each year

 

Hospice Part A coinsurance

Hospital Part A coinsurance plus coverage for 365 add’l days after Medicare benefits end,

 

100% Part B coinsurance,

 

First three pints of blood each year

 

Hospice Part A coinsurance

Hospital Part A coinsurance plus coverage for 365 add’l days after Medicare benefits end,

 

100% Part B coinsurance,*

 

First three pints of blood each year

 

Hospice Part A coinsurance

Hospital Part A coinsurance plus coverage for 365 add’l days after Medicare benefits end,

 

100% Part B coinsurance,

 

First three pints of blood each year

 

Hospice Part A coinsurance

Hospitalization and preventive care paid at 100%; other basic benefits paid at 50%

Hospitalization and preventive care paid at 100%; other basic benefits paid at 75%

Hospital Part A coinsurance plus coverage for 365 add’l days after Medicare benefits end,

 

Part B coinsurance,

 

First three pints of blood each year,

 

Hospice Part A coinsurance

Hospital Part A coinsurance plus coverage for 365 add’l days after Medicare benefits end,

Part B coinsurance, except up to $20 copayment for office visit, and up to $50 copayment for ER,

First three pints of blood each year,

Hospice Part A coinsurance

 

 

Skilled Nursing Facility Coinsurance

Skilled Nursing Facility Coinsurance

Skilled Nursing Facility Coinsurance

Skilled Nursing Facility Coinsurance

50% Skilled Nursing Facility Coinsurance

75% Skilled Nursing Facility Coinsurance

Skilled Nursing Facility Coinsurance

Skilled Nursing Facility Coinsurance

 

Part A Deduct.

Part A Deduct

Part A Deduct.

Part A Deduct.

Part A Deduct.

50% Part A Deduct.

75% Part A Deduct.

50% Part A Deduct.

Part A Deduct.

 

 

Part B Deduct.

 

Part B Deduct.

 

 

 

 

 

 

 

 

 

Part B Excess (100%)

Part B Excess (100%)

 

 

 

 

 

 

 

Foreign Travel Emergency

Foreign Travel Emergency

Foreign Travel Emergency

Foreign Travel Emergency

 

 

 

Out of pocket limit $[  ]; paid at

100% after limit

reached

 

 

 

Out of pocket limit $[  ]; paid at

100% after limit

reached

Foreign Travel Emergency

Foreign Travel Emergency

 

***Deductible amounts and out-of-pocket limits announced annually by CMS.

*Plan F also has an option called a high deductible Plan F. This high deductible plan pays the same benefits as Plan F after having paid a calendar year ($***) deductible.  Benefits from high deductible Plan F will not begin until out-of-pocket expenses exceed ($***).  Out-of-pocket expenses for this deductible are expenses that would ordinarily be paid by the policy. These expenses include the Medicare deductible for Part A and Part B, but do not include the plan’s separate foreign travel emergency deductible.     

Medicare and the New Health Law & What it means for you
Added ›05/27/2010 9:13:50 AM

“Medicare and the New Health Law – What it Means for You”


Starting tomorrow and throughout this week, Medicare beneficiaries across the country should begin receiving copies of a brochure “Medicare and the New Health Law – What it Means for You” in their mailboxes. The mailing from CMS outlines key provisions of the Affordable Care Act for people with Medicare as well as members of their families. The mailing is being sent in both English and Spanish.

Because Medicare is a trusted resource for beneficiaries and their family members, the mailing encourages them to log on to www.medicare.gov or call 1-800-MEDICARE to get their questions about Medicare or the Affordable Care Act answered and reminds them to be on the alert for possible scams.

The first benefit that many people with Medicare will receive as a result of the passage of the new law is a one-time check for $250, if they enter the Part D donut hole and are not eligible for Medicare Extra Help. Beginning next year, the Affordable Care Act ensures that Medicare beneficiaries will get free preventive care services like colorectal cancer screening and mammograms, in addition to a free annual wellness visit. The law also includes new tools to help fight fraud by helping Medicare crack down on criminals who are seeking to scam seniors and steal taxpayer dollars.

The brochures can also be found at: http://www.medicare.gov/Publications/Pubs/pdf/11467.pdf (English) and http://www.medicare.gov/Publications/Pubs/pdf/11467_S.pdf (Spanish
More Coverage Gap Info from the Center for Medicare and Medicaid Services
Added ›05/27/2010 9:05:27 AM

Closing the Prescription Drug Coverage Gap
You Could Be Eligible For
A $250 Rebate This Year
to Help with your Medicare Drug Costs


The Affordable Care Act passed by Congress and signed by President Obama this year contains some important benefits for Medicare recipients.
If you have Medicare prescription drug coverage, and aren’t already getting Medicare Extra Help, Medicare will automatically send you a one-time $250 rebate check after you reach the coverage gap (also called the “donut hole”) in 2010. This rebate is the first step toward closing the Medicare prescription drug coverage gap.
What is the coverage gap and how will I know if I’ve reached it?
Most Medicare drug plans have a coverage gap. This means that after you and your plan have spent a certain amount of money for covered drugs, you have to pay all costs out-of-pocket for your drugs (up to a limit).
The Explanation of Benefits notice, which your drug plan mails to you each month when you fill a prescription, will tell you how much you’ve spent on covered drugs and whether you’ve entered the coverage gap.
Will I need to do anything to get this rebate check?
No. There are no forms to fill out. Medicare will automatically send a check that’s made out to you. You don’t need to provide any personal information like your Medicare, Social Security, or bank account numbers to get the rebate check. Don’t give your personal information to anyone who calls you about the $250 rebate check. Call 1-800-MEDICARE (1-800-633-4227) to report anyone who does this. TTY users should call 1-877-486-2048.
When will I get the rebate check?
If you reach the coverage gap this year and enter the Part D “donut hole”, you will receive a one-time $250 rebate check if you are not already receiving Medicare Extra Help. These checks will begin to get mailed to beneficiaries starting in mid-June.
Checks will be mailed monthly throughout the year as beneficiaries enter the coverage gap. However, this is a one-time benefit and beneficiaries who qualify will only receive one check after they reach the coverage gap.
What if I don’t get the rebate check when I should?
Beneficiaries who hit the donut hole after the program has begun should expect to receive their check within 45 days. Your rebate may be delayed if Medicare doesn’t have information from your Medicare drug plan showing that you reached the coverage gap in time to include you in the next mailing. You should call your Medicare drug plan to make sure all of your information has been sent to Medicare.
If you don’t get your rebate check, contact Medicare. Individuals receiving Medicare Extra Help will not receive a rebate check.
You can also check to make sure Social Security has your correct home address. Call 1-800-772-1213 or your local Social Security office. TTY users should call 1-800-325-0778.

What’s Next ….Coming in 2011
If you reach the coverage gap in 2011, you may get a 50% discount on your brand name prescription drugs at the time you buy them. Stay tuned for more information from Medicare.
Help us spread the word about this important benefit
And help stop scams against seniors
Pass this brochure along to your friends, neighbors and family so they know the facts about this important program. Remember- there are no forms to fill out to receive this benefit once you qualify for it. Medicare will automatically send a check that’s made out to you.
You don’t need to provide any personal information like your Medicare, Social Security, or bank account numbers to get the rebate check. Don’t give your personal information to anyone who calls you about the $250 rebate check. Call 1-800-MEDICARE (1-800-633-4227) to report anyone who does this. TTY users should call 1-877-486-2048.
Go to stopmedicarefraud.gov to learn more about how Medicare is working with law enforcement to stop scams against seniors.
Have other questions about the $250 rebate check or the Affordable Care Act and Medicare?
Please refer to the brochure Medicare and the New Health Care Law--What it Means for You that Medicare has sent you. You can also visit www.medicare.gov, or call 1-800-MEDICARE.

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